Kickoff Sunday, Sep 8th 4:05pm Eastern

Colts (
19.25) at

Chargers (
25.25)

Over/Under 44.5

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Notes

Key Matchups
Colts Run D
32nd DVOA/19th Yards allowed per carry
Chargers Run O
24th DVOA/27th Yards per carry
Colts Pass D
24th DVOA/17th Yards allowed per pass
Chargers Pass O
13th DVOA/4th Yards per pass
Chargers Run D
25th DVOA/22nd Yards allowed per carry
Colts Run O
10th DVOA/4th Yards per carry
Chargers Pass D
25th DVOA/5th Yards allowed per pass
Colts Pass O
12th DVOA/27th Yards per pass

No game has seen its complexion change more over the last month than this one. The Melvin Gordon holdout has continued throughout the preseason. Derwin James is out for most of the year, removing one of the NFL's elite defensive playmakers from the equation in this game. And then…yeah, Andrew Luck retired two weeks before the start of the season.

Last season, the Colts played at the fastest pace in the NFL (the Chargers, by the way, played at the slowest pace), but Frank Reich is one of the four or five most adaptable coaches in the NFL . . .

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