Kickoff Sunday, Sep 13th 4:25pm Eastern

Cards (
20.5) at

49ers (

Over/Under 47.5


Key Matchups
Cardinals Run D
30th DVOA/26th Yards allowed per carry
49ers Run O
3rd DVOA/6th Yards per carry
Cardinals Pass D
31st DVOA/17th Yards allowed per pass
49ers Pass O
1st DVOA/1st Yards per pass
49ers Run D
18th DVOA/8th Yards allowed per carry
Cardinals Run O
15th DVOA/3rd Yards per carry
49ers Pass D
3rd DVOA/2nd Yards allowed per pass
Cardinals Pass O
27th DVOA/29th Yards per pass

In Week 1, against Rivera, Zimmer, & Bowles defenses, Kyle Shanahan is 1-2 with 8 total turnovers and as many defensive touchdowns (2), as total offensive touchdowns (2)In Kyle Shanahan’s only career matchup vs HC Vance Joseph (DEN HC), his 49ers won 20-14 behind 332 passing yards from Nick Mullens and a career day (210 yards) from George KittleAgainst Joseph’s ARI defense in 2019, Shanahan’s offense scored 28 and 30 points despite missing Kittle for the second gameAgainst ARI in 2019: Garoppolo’s 2nd & 3rd highest pass attempt totals, 1st & 3rd highest . . .

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